PEPTIDE MODIFICATIONS

USV Peptide synthesis offers the following peptide modifications:

Protection

  • Fmoc
  • Boc
  • Full Protection (C'- Term free)
  • CBZ
  • Cys (Acm), Cys (tBu)

N-Terminal Modifications

  • Acetylation
  • Formylation
  • Fatty Acid
  • Myristic Acid
  • Palmytolyl
  • DTPA
  • HYNIC

C-Terminal Modifications

  • Amidation
  • pNA
  • FAMC
  • Succinylation
  • NHS
  • CMK/FMK

Special Amino Acids

  • D-Ile, D-Arg, D-Cys, D-Asp, D-Asn, D-Glu, D-Gln, D-Ser,
  • D-His,D-Thr, D-Trp, D-Lys, D-Tyr, D-Orn, Orn, Abu, Aib, (D)1-Nal. (D)2-Pal, (D)4-Cl-Phe, Nva, Nle, Hse, Hcy, Pen, Mpa
  • N-Methyl amino acid

Phosphorylation

  • Phospho Serine
  • Phospho Tyrosine
  • Phospho Threonine

Quenched Fluorescent Peptide

  • EDANS/ DABCYL

Fluorescence / Dye labeling

  • Biotin (N-Term, Y/N Ahx)
  • Biotin (Lys w/wo Lys)
  • FITC/ 5-FAM (N-Term, Y/N Ahx)
  • Dansyl (N-Term, Y/N Ahx)
  • MCA (N-Term)
  • AMC (C-Term)
  • HYNIC
  • DTPA
  • DTPA

Cyclic Peptide

  • Disulfide bridge 1
  • Disulfide bridge 2
  • Disulfide bridge 3
  • Amide cyclic
  • Lactam Bridge
  • Backbone cyclisation

Protein Conjugation

  • Asymmetric 4 branches
  • Asymmetric 8 branches

Multiple Antigenic Peptide

  • KLH
  • BSA



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